A first course in systems biology

Abstract

1. Biological systems -- 2. Introduction to mathematical modeling -- 3. Static network models -- 4. The mathematics of biological systems -- 5. Parameter estimation -- 6. Gene systems -- 7. Protein systems -- 8. Metabolic systems -- 9. Signaling systems -- 10. Population systems -- 11. Integrative analysis of genome, protein, and metabolite data: a case study in yeast -- 12. Physiological modeling: the heart as an example -- 13. Systems biology in medicine and drug development -- 14. Design of biological systems -- 15. Emerging topics in systems biology.