Bioinformatics and functional genomics

Abstract

Part I. Analyzing DNA, RNA, and protein sequences -- 1. Introduction -- 2. Access to sequence data and related information -- 3. Pairwise sequence alignment -- 4. Basic local alignment search tool (BLAST) -- 5. Advanced database searching -- 6. Multiple sequence alignment -- 7. Molecular phylogeny and evolution -- Part II. Genomewide analysis of DNA, RNA and protein -- 8. DNA: The Eukaryotic Chromosome -- 9. Analysis of Next-Generation Sequence Data -- 10. Bioinformatic Approaches to Ribonucleic Acid (RNA) -- 11. Gene Expression: Microarray and RNA-seq Data Analysis -- 12. Protein Analysis and Proteomics -- 13. Protein Structure -- 14. Functional Genomics -- Part III. Genome analysis -- 15. Genomes Across the Tree of Life -- 16. Completed Genomes: Viruses -- 17. Completed Genomes: Bacteria and Archaea -- 18. Eukaryotic Genomes: Fungi -- 19. Eukaryotic Genomes: From Parasites to Primates -- 20. Human Genome -- 21. Human Disease.